Which neural connectivity pattern is proposed in autism spectrum disorder related to social processing?

Which neural connectivity pattern is proposed in autism spectrum disorder related to social processing?

• A. Underconnectivity between social brain networks
• B. Hyperconnectivity of all brain networks
• C. Normal connectivity with localized deficits
• D. Universal disconnection of motor networks

Answer: (A)

Reduced long-range functional connectivity among social brain regions is the pattern proposed for autism's social processing differences. The social brain relies on coordinated activity between areas like the fusiform face area (face processing), posterior superior temporal sulcus and temporoparietal junction (gaze, intention, and biological motion), amygdala (emotional salience), and medial prefrontal cortex (thinking about others). In autism, these distant regions often show weaker synchronization, meaning information about social cues isn’t integrated as smoothly across the network. This underconnectivity helps explain why people with autism may have difficulties recognizing faces, interpreting others’ thoughts or emotions, and integrating social signals in real time. It’s not a blanket hyperconnectivity of all networks, nor normal connectivity with isolated deficits, nor a universal disconnection of motor networks—the social-specific long-range underconnectivity best fits the observed pattern in social processing.

Reduced long-range functional connectivity among social brain regions is the pattern proposed for autism's social processing differences. The social brain relies on coordinated activity between areas like the fusiform face area (face processing), posterior superior temporal sulcus and temporoparietal junction (gaze, intention, and biological motion), amygdala (emotional salience), and medial prefrontal cortex (thinking about others). In autism, these distant regions often show weaker synchronization, meaning information about social cues isn’t integrated as smoothly across the network. This underconnectivity helps explain why people with autism may have difficulties recognizing faces, interpreting others’ thoughts or emotions, and integrating social signals in real time. It’s not a blanket hyperconnectivity of all networks, nor normal connectivity with isolated deficits, nor a universal disconnection of motor networks—the social-specific long-range underconnectivity best fits the observed pattern in social processing.